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Colchicum autumnale, Meadow saffron, Colchicum


Colchicum autumnale, Meadow saffron

Constituents
alkaloids (colchicine), flavenoids

Pharmacology
inhibits phagocytosis of uric acid crystals by leukocytes
(does not increase elimination of uric acid)
mitotic poison - prevents spindle formation and function

Actions
anti-inflammatory, teratogenic

Uses
acute gout

Dose
tincture 10-15 gtt every hour during acute attack

Cautions
highly toxic, teratogenic CI pregnancy

 

 

 

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