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Molybdenum


Functions
cofactor for redox reactions
sulfite oxidase - degrades cysteine and methionine
xanthene oxidase - terminal oxidation of purines into uric acid
aldehyde oxidase - detoxification of alcohol

Requirements
ESADDI - 75-250 ug qd

Sources
germ of grains and legumes

Deficiency
rare

Therapeutics
asthma - may be due to a decreased sulfite oxidase function
hypouricemia - cofactor for xanthene oxidase (purines -> uric acid)
lupus - some have high sulfites in the urine
rheumatism
Wilson's syndrome
dental carrie prevention
cancer prevention

Toxicity
high levels may precipitate gout by increasing uric acid levels

Interactions
molybdenum increases copper excretion, and vice-versa



 

 

 

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