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| Chlorothalidone, Hygroton, Thalitone Description Chlorothalidone is a thiazide diuretic. Action antihypertensive, thiazide diuretic Indications Side Effects agranulocytosis, anorexia, aplastic anemia, azotemia, constipation, diarrhea, dizziness, exfoliative dermatitis, glycosuria, headache, hypercalcemia, hypercholesterolemia, hyperglycemia, hypertriglyceridemia, hyperuricemia, hypochloremia, hypokalemia, hypomagnesemia, hyponatremia, impotence, jaundice, leukopenia, libido decrease, muscle cramping, nausea/vomiting, orthostatic hypotension, pancreatitis, pancytopenia, paresthesias, photosensitivity, polyuria, restlessness, Stevens-Johnson syndrome, thrombocytopenia, toxic epidermal necrolysis, vertigo, weakness, xanthopsia, Drug-Vitamin-Herb Interactions Negative interactions: Calcium Thiazide diuretics promote calcium retention, which increases levels. Licorice Licorice contains glycyrrhizin which promotes potassium loss, adding to the side effects of thiazide diuretics. St JohnÕs Wort and Dong quai St JohnÕs Wort and Dong quai may cause sensitivity to sunlight, adding to side effect of loop diuretics. Positive interactions: Magnesium, Potassium and Zinc Thiazide diuretics promote magnesium, potassium and zinc loss, possibly leading to deficiency.
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