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Donepezil, Aricept Description Donepezil is a centrally acting reversible acetyl cholinesterase inhibitor that is used is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. Action inhibits acetylcholinesterase in CNS Indications Side Effects At least 2% of patients receiving 5mg/day experienced nausea, diarrhea, and vomiting. At least 5% of patients receiving 10mg/day experienced nausea, diarrhea, insomnia, vomiting, muscle cramps, fatigue, and anorexia. Body as a Whole: Headache, pain (various locations), accident, fatigue, influenza, chest pain, toothache, fever, edema face, periorbital edema, hernia hiatal, abscess, cellulitis, chills, generalized coldness, head fullness, listlessness Cardiovascular System: Syncope, hypertension, vasodilation, atrial fibrillation, hot flashes, hypotension, angina pectoris, postural hypotension, myocardial infarction, AV block (first degree), congestive heart failure, arteritis, bradycardia, peripheral vascular disease, supraventricular tachycardia, deep vein thrombosis Digestive System: Nausea, Diarrhea, Vomiting, Anorexia, fecal incontinence, gastrointestinal bleeding, bloating, epigastric pain, eructation, gingivitis, increased appetite, flatulence, periodontal abscess, cholelithiasis, diverticulitis, drooling, dry mouth, fever sore, gastritis, irritable colon, tongue edema, epigastric distress, gastroenteritis, stomach ulcer Endocrine: diabetes mellitus, goiter Hemic and Lymphatic System: Ecchymosis, anemia, thrombocythemia, thrombocytopenia, eosinophilia, erythrocytopenia Metabolic and Nutritional Systems: Weight Decrease, dehydration, gout, hypokalemia, increased creatine kinase, hyperglycemia, weight increase, increased lactate dehydrogenase Musculoskeletal System: Muscle Cramps, Arthritis, bone fracture, muscle weakness, muscle fasciculation Nervous System: Insomnia, Dizziness, Depression, Abnormal Dreams, Somnolence, delusions, tremor, irritability, paresthesia, aggression, vertigo, ataxia, increased libido, restlessness, abnormal crying, nervousness, aphasia, cerebrovascular accident, intracranial hemorrhage, transient ischemic attack, emotional lability, neuralgia, coldness (localized), muscle spasm, dysphasia, hostility, decreased libido, melancholia, emotional withdrawal, nystagmus, pacing Respiratory System: Dyspnea, sore throat, bronchitis, epistaxis, postnasal drip, pneumonia, hyperventilation, pulmonary congestion, wheezing, hypoxia, pharynglitis, pleuisy, pulmonary collapse, sleep apnea, snoring Skin and Appendages: Pruritus, diaphoresis, urticaria, dermatitis, erythema, skin discoloration, hyperkeratosis, alopecia, fungal dermatitis, herpes zoster, hirsutism, skin striae, night sweats, skin ulcer Special Senses: Cataract, eye irritation, vision blurred, dry eyes, glaucoma, earache, tinnitus, blepharitis, decreased hearing, retinal hemorrhage, otitis externa, otitis media, bad taste, conjunctival hemorrhage, ear buzzing, motion sickness, spots before eyes Urogenitial System: Frequent Urination, urinary incontinence, nocturia, dysuria, hematuria, urinary urgency, metrorrhagia, cystitis, enuresis, prostate hypertrophy, pyelonephritis, inability to empty bladder, breast fibroadenosis, fibrocystic breast, mastitis, pyuria, renal failure, vaginitis Other Side Effects: Abdominal pain, agitation, cholecystitis, confusion, convulsions, hallucinations, heart block, hemolytic anemia, hyponatremia, pancreatitis, and rash Drug-Vitamin-Herb Interactions
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Fantastic new books! CAM Therapies has studies on natural therapies for over 100 diseases. CAM Labs lists lab tests for 100 diseases. Nutritional Genetics is a fantastic resource.
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