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Grepafloxacin, Raxar Description Grepafloxacin is a fluoroquinolone antibiotic. Grepafloxacin was withdrawn in the United States due to its side effect of lengthening the QT interval on the electrocardiogram, leading to cardiac events and sudden death. Action antibiotic, fluoroquinolone, withdrawn Indications Side Effects Drug-Vitamin-Herb Interactions Negative interactions: Fennel Fennel may reduce levels of ciprofloxacin, possibly impairing its effectiveness. St JohnÕs Wort and Dong quai St JohnÕs Wort and Dong quai increase sensitivity to sunlight, adding to the side effect oc fluoroquinolones. Calcium Calcium may interfere with absorption. Take at a different time of day. Iron Iron may interfere with absorption. Take at a different time of day. Zinc Zinc may interfere with absorption. Take at a different time of day. Positive interactions: Lactobacillus acidophilus Probiotics replace normal intestinal bacteria, which may reduce the side effect of diarrhea associated with antibiotics. Sacchromyces boulardii Sacchromyces boulardii may prevent antibiotic-related diarrhea. Vitamin K Antibiotics may cause vitamin K deficiency by destroying the beneficial bacteria that produce it.
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