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| Hydrochlorothiazide, HCTZ, Esidrix, HydroDIURIL, Oretic Description Hydrochlorothiazide is a diuretic drug that acts by inhibiting the kidney's ability to retain water, which reduces the volume of the blood, decreasing peripheral vascular resistance. Action antihypertensive, thiazide diuretic Indications diabetes insipidus, edema, hypercalciuria, hypertension, premenstrual syndrome (PMS), Side Effects agranulocytosis, anorexia, aplastic anemia, azotemia, blurred vision, constipation, diarrhea, dizziness, exfoliative dermatitis, glycosuria, headache, hemolysis, hypercalcemia, hypercholesterolemia, hyperglycemia, hypertriglyceridemia, hyperuricemia, hypochloremia, hypokalemia, hypomagnesemia, hyponatremia, hypotension, impotence, interstitial nephritis, jaundice, leukopenia, nausea/vomiting, orthostatic hypotension, pancreatitis, pancytopenia, paresthesias, photosensitivity, polyuria, Stevens-Johnson syndrome, toxic epidermal necrolysis, vertigo, weakness, xanthopsia, Hyponatremia (low sodium): confusion; convulsions; decreased mentation; fatigue; irritability; muscle cramps Hypokalemia (low potassium): dryness of mouth; increased thirst; irregular heartbeat; mood or mental changes; muscle cramps or pain; nausea or vomiting; unusual tiredness or weakness; weak pulse Agranulocytosis (low neutrophils, eosinophils, basophils): fever or chills; cough or hoarseness; lower back or side pain; painful or difficult urination Thrombocytopenia: unusual bleeding or bruising; black, tarry stools; blood in urine or stools; pinpoint red spots on skin Orthostatic hypotension: dizziness or lightheadedness when getting up from a lying or sitting position Gout or hyperuricemia: joint pain, lower back or side pain Drug-Vitamin-Herb Interactions Negative interactions: Calcium Thiazide diuretics promote calcium retention, which increases levels. Licorice Licorice contains glycyrrhizin which promotes potassium loss, adding to the side effects of thiazide diuretics. St JohnÕs Wort and Dong quai St JohnÕs Wort and Dong quai may cause sensitivity to sunlight, adding to side effect of loop diuretics. Positive interactions: Magnesium, Potassium and Zinc Thiazide diuretics promote magnesium, potassium and zinc loss, possibly leading to deficiency.
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Fantastic new books! CAM Therapies has studies on natural therapies for over 100 diseases. CAM Labs lists lab tests for 100 diseases. Nutritional Genetics is a fantastic resource.
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