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| Levodopa, Dopar, Larodopa Description Levodopa is an intermediate in dopamine biosynthesis used in the management of Parkinson's disease. Action dopamine Indications Larodopa is indicated in the treatment of idiopathic Parkinson's disease (Paralysis Agitans), postencephalitic parkinsonism, symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication, and manganese intoxication. It is indicated in those elderly patients believed to develop parkinsonism in association with cerebral arteriosclerosis. Side Effects Choreiform or dystonic movements, anorexia, nausea/vomiting, xerostomia, dysphagia, dysgeusia, sialorrhea, ataxia, increased hand tremor, headache, dizziness, numbness, weakness, faintness, bruxism, confusion, insomnia, nightmares, hallucinations, delusions, agitation, anxiety, malaise, fatigue, euphoria, cardiac arrhythmias, orthostatic hypotension, elevated hepatic enzymes., Drug-Vitamin-Herb Interactions Negative interactions: 5-HTP The combination of 5-HTP and carbidopa may cause a scleroderma-like condition. Branched Chain Amino Acids, BCAAs Amino acids in dietary proteins decrease effectiveness of levodopa. Iron Iron interferes with absorption of carbodopa and levodopa. Take at separate times. Kava Kava may interfere with the action of dopamine. Vitamin B6 Higher doses of Vitamin B6 can reduce the therapeutic effect of levodopa alone in ParkinsonÕs disease. Mixed interactions: SAMe Levodopa may deplete SAMe.
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