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| Lisinopril, Prinivil, Zestril, Lisodur Description Lisinopril is an ACE inhibitor. It is primarily used in treatment of hypertension, congestive heart failure, heart attacks and also in preventing renal and retinal complications of diabetes. Lisinopril is the lysine-analog of enalapril. Action ACE inhibitor Indications post-myocardial infarction, diabetic nephropathy, heart failure, hypertension, proteinuria, Side Effects angioedema, azotemia, cough, dizziness, fatigue, headache, hyperkalemia, hypotension, orthostatic hypotension, sinus tachycardia, syncope, Drug-Vitamin-Herb Interactions Negative interactions: Arginine High doses of arginine may alter potassium levels. ACE Inhibitors may cause potassium retention. Iron Iron can interfere with absorption of ACE Inhibitors. Take at a different time of day. Licorice Licorice can cause sodium retention and raise blood pressure, which may counteract the actions of ACE Inhibitors. Potassium ACE Inhibitors may cause potassium retention, possibly resulting in hyperkalemia (excess potassium). St JohnÕs Wort and Dong Quai St JohnÕs Wort and Dong Quai can cause increased sensitivity to the sun, adding to side effect of ACE inhibitors. Positive interactions: Zinc ACE inhibitors cause depletion of zinc. Zinc supplements may help prevent this.
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