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Paroxetine, Paxil, Seroxat, Aropax, Pondera, Deroxat

Description

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It is one of the most prescribed antidepressants on the market due to its efficacy in treating depression as well as a spectrum of anxiety disorders ranging from panic attacks to phobias.

Paroxetine is approved to treat the symptoms of depression, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), panic disorder, generalized anxiety disorder (GAD), social phobia/social anxiety disorder, and premenstrual dysphoric disorder (PMDD).

Unapproved uses include: premature ejaculation, chronic headache, and bipolar disorder. It may also reduce the symptoms of diabetic neuropathy

Action

SSRI (Selective serotonin uptake inhibitor)

Indications

major depression, obsessive-compulsive disorder, panic disorder,

Side Effects

agitation, angioedema, anorexia, anxiety, appetite stimulation, asthenia, confusion, constipation, diaphoresis, diarrhea, dizziness, dysgeusia, dyspepsia, dysuria, ejaculation dysfunction, erythema nodosum, flatulence, headache, hyponatremia, hypotension, impotence, increased urinary frequency, insomnia, libido decrease, maculopapular rash, mania, myalgia, myasthenia, myopathy, nausea/vomiting, orgasm dysfunction, orthostatic hypotension, palpitations, paresthesias, SIADH, tremor, urticaria, xerostomia,

Drug-Vitamin-Herb Interactions


Negative interactions:

5-HTP
5-HTP increases levels of serotonin, which increases the risk of serotonin syndrome.

SAMe
SAMe increases levels of serotonin, which increases the risk of serotonin syndrome.

St JohnÕs Wort
St JohnÕs Wort may increase levels of serotonin, which increases the risk of serotonin syndrome.


Positive interactions:

Ginkgo biloba
Ginkgo may help reverse the sexual side effects of SSRIs, including inability to orgasm in women and impotence in men.

 

 

 

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