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Sulfasalazine, Azulfidine, Salazopyrin, SAS-500

Description

Sulfasalazine is an NSAID.

Action

NSAID

Indications



Side Effects

agranulocytosis, diarrhea, dizziness, elevated hepatic enzymes, fever, headache, hemolytic anemia, hepatitis, nausea/vomiting, neutropenia, oligospermia, photosensitivity, pruritus, skin discoloration, Stevens-Johnson syndrome, toxic epidermal necrolysis, urine discoloration, urticaria,

Drug-Vitamin-Herb Interactions


Negative interactions:

Arginine
Arginine stimulates gastrin production which increases stomach acid. This can irritate the stomach.

Feverfew
Feverfew has similar actions. Combining Feverfew with NSAIDs may increase the risk of side effects.

Natural blood thinners: Garlic, Ginkgo, Vitamin E, Policosanol, Dong quai, Ginger, Horse chestnut, Red clover, Fish oils, and OPCs.
Natural blood thinners may increase the tendency to bleed, a side effect of NSAIDs.

Potassium, magnesium, and calcium citrate
Citrates alkalinize the urine which decrease the therapeutic effect of NSAIDs and ASA.

St JohnÕs Wort and Dong quai
St JohnÕs Wort and Dong Quai can cause sensitivity to sunlight, which may add to side effects of NSAIDs.


Positive interactions:

Cayenne
Cayenne may help prevent gastric bleeding.

Colostrum
Colostrum may help protect against ulcers caused by NSAIDs.

Folate
Folate may be depleted by NSAIDs.

Licorice (DGL)
Licorice (DGL) may help protect the stomach against gastric damage caused by NSAIDs.

Vitamin C
Vitamin C may be depleted by NSAIDs.

 

 

 

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Nutritional Genetics is a fantastic resource.

 

 

 

 

 

 


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