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| Triamterene, Dyrenium Description Triamterene is a potassium sparing diuretic. Action potassium sparing diuretic Indications edema, hypertension, hypokalemia, premenstrual syndrome (PMS), Side Effects azotemia, diarrhea, dizziness, fatigue, headache, hyperkalemia, hypomagnesemia, hyponatremia, interstitial nephritis, jaundice, megaloblastic anemia, muscle cramping, nausea/vomiting, nephrolithiasis, photosensitivity, polyuria, thrombocytopenia, weakness, xerostomia, Drug-Vitamin-Herb Interactions Negative interactions: Arginine High doses of arginine may alter potassium levels. Licorice Licorice causes the body to lose potassium, which may counteract the drug action. Magnesium Potassium-sparing diuretics may cause magnesium retention. Potassium Potassium supplementation raise the levels too high. Positive interactions: Folate Triamterene is structurally similar to folate. Higher doses deplete folic acid.
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